Business Impacts
80% reduction in pipeline execution time
Improved performance and scalability
Reduced time and effort by leveraging terraform templates
Customer Key Facts
- Country : US East
- Industry : Healthcare
Problem Context
The client is a drug discovery company that wants to accelerate the development of allosteric drug therapies to identify drug regulatory hotspots.
The client sought to build their DNA Encoded Library (DEL) Pipeline on a cloud-native platform. The client also wanted to accelerate the process of building their protein libraries and reduce the management overhead by leveraging High Performance Computing on Google Cloud.
Challenges
- Existing pipeline required more than 35 days to run tasks for 25 million molecules
- Unable to run heavy computing workloads on the same HPC cluster
- Long and complicated setup time for CompChem
Technologies Used
Compute Engine
SLURM
Pub/Sub
Cloud Storage
Cloud Functions
Firestore
Cloud SQL
Building DNA-encoded Library (DEL) on a cloud-native platform
Solution
- Quantiphi helped client develop a pilot environment and set up a SLURM-based HPC cluster that houses a DNA-encoded library pipeline in a cloud-native manner
- Quantiphi also assisted the client by providing terraform scripts to automate their project setup
Results
- Ease of management and operability
- Significant acceleration in pipeline with the execution time reduced from 35 days to under 6 days for 25 million molecules
- One-click deploy solution developed using Terraform, allowing the client to delete High Perfromance Computing clusters as required
- Fault tolerant and highly available solution designed with the High Performance Computing cluster designed in a shared environment, allowing teams to utilize the cluster
